Searchable abstracts of presentations at key conferences in endocrinology

ea0029p41 | Adrenal cortex | ICEECE2012

Cancer induces adrenal and pituitary alterations during the development of cachexia-anorexia syndrome

Mazzuco T. , Crespigio J. , Fonseca E. , Macioszek M. , Lazari-Berbel L. , de Freitas R. , Souza H.

Introduction: Tumour cachexia-anorexia syndrome (CAS) is a complex disorder characterized by progressive nutritional and metabolic alterations that lead to loss of muscle and adipose tissue observed in advanced-stage cancer. CAS indicates unfavourable prognosis, regardless of cancer type. Under the influence of permanent aggression, we have evaluated the effects of the cancer cachexia development on the hypothalamic-pituitary-adrenal (HPA) axis.Methods: ...